Praha Florenc Bus Station is the main terminal for international coach arrivals into Prague. It is also the most central of the transport hubs for internal bus travel throughout the Czech Republic.
Praha Florenc Bus Station is located just outside Prague's city centre, in an area called Florenc, so most travellers arriving with luggage take public transport onto their accommodation. Taxis are also an option.
Florenc has a metro station situated right next to the bus station, and a tram stop. So you'll be able to continue your onward journey swiftly - not a bad thing, as Florenc is not the most beautiful part of Prague!
From Florenc metro it is just stops to either Muzeum (top of Wenceslas Square) or Mustek (bottom of Wenceslas Square, and 5 minutes walk from the Old Town Square).
Facilities at the bus station include an exchange office, internet café, fast-food, left-luggage, WC and showers, and a kiosk selling public transport tickets, maps and guides. The nearest cashpoint (ATM) is at Florenc metro station.